Melicope remyi is a shrub or shrubby tree growing 1–3 meters tall, featuring leafy branches toward the apex and exhibiting a glabrous or yellowish-brown pubescence on new growth and inflorescences. The stems are densely glandular punctate and emit a pepsin-like odor when freshly broken. The leaves are simple and opposite, with obovate to broadly spatulate blades measuring 14–40 cm in length and 4.5–18.5 cm in width. The apex of the leaves is rounded to subacute, with a narrowly cuneate base, and transitions abruptly to rounded, subtruncate, or subauriculate at the juncture to the petiole. The upper surfaces of the leaves are glabrous, while the lower surfaces are sparsely puberulent when young and glandular punctate. The flowers appear in axillary cymes of 1 to 3 (possibly up to 5), with peduncles and pedicels supporting the floral structure. The flowers are bisexual (perfect) and actinomorphic, featuring a calyx of four sepals and a corolla of four white or cream petals. The stamens are eight in number and nearly completely connate into a staminal tube with elongated anthers. The ovary is superior and 4-carpellate, leading to subglobose fruit 20–30 mm in diameter, minutely puberulent, and 4-lobed. These fruits are 20–30 mm in diameter; 4–4-lobed; minutely puberulent; carpels erect; connate throughout; separating at various places during development; apex rounded. The seeds are 5–8 per cell; 8-10 mm long; funicles short; endocarp glabrous; embryo with thin; broad; rounded cotyledons; hypocotyl very short; embedded in the white endosperm. It is native to wet forests between 820 – 1,080 meters.